Saturday, March 29, 2008



Non Stimulant Treatment for Children

Italian researchers have been on the lookout for a non stimulant form of medication to treat a form of hereditary mental retardation known as Fragile X Syndrome (FXS). FXS affects many children and is oftentimes accompanied by attention deficit disorder and attention deficit hyperactivity disorder. While stimulant drugs such as Ritalin do help with the disease, they also cause negative side effects for many children, such as social withdrawal, decreased verbal expression and irritability.

In the quest for a non-stimulant drug, researchers studied over 50 boys ages 6-12 with FXS and ADHD. Some of the boys took a placebo two times a day for 12 months, while others took 500 milligrams of L-acetyl carnitine (LAC).

Results showed that the patients who took LAC had improved social skills, increased attention and focus and reduced hyperactive behavior.

The placebo group showed a slightly similar trend, but the LAC group showed a much higher rate of change.

The researchers are suggesting that the amino acid be used for treating Fragile X Syndrome, but research and studies will be ongoing.




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